Browsing by Author "Jakobsen, Lisa"

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    • Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism 

      Jakobsen, Lisa; Frischmuth, Tobias; Brækkan, Sigrid Kufaas; Hansen, John Bjarne; Morelli, Vania Maris (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-31)
      Background - A high mean platelet volume (MPV), a marker of increased platelet reactivity, is a risk factor for venous thromboembolism (VTE). Whether established prothrombotic single nucleotide polymorphisms (SNPs) further increase the VTE risk in subjects with high MPV because of biological interaction remains unknown.<p> <p>Aim - To investigate the joint effect of high MPV and prothrombotic ...

    • Mean platelet volume (MPV) and incident myocardial infarction and ischemic stroke: A Literature Review 

      Jakobsen, Lisa (Master thesis; Mastergradsoppgave, 2023-06-01)
      Background: Myocardial infarction (MI) and ischemic stroke (IS) are leading causes of death worldwide. Traditional risk factors, including hypertension, dyslipidemia, smoking and diabetes, account for the majority of the MI and IS cases. However, the disease burden remains substantial, and research for discovering novel risk factors has been ongoing, and large platelets can be a potential candidate. ...